BIOL 230 Lecture Guide - The Classical Complement Pathway: Cleavage of C2 by C1

Fig. 3A: Cleavage of C2 by C1 during the Classical Complement Pathway - Step 1

C2 binds to the C4b and the enzyme C1 subsequently cleaves C2 into C2a and C2b. The C4b2a functions as a C3 convertase that can enzymatically cleave hundreds of molecules of C3 into C3a and C3b.

Illustration of Cleavage of C2 by C1 during the Classical Complement Pathway - Step 1 .jpg by Gary E. Kaiser, Ph.D.
Professor of Microbiology, The Community College of Baltimore County, Catonsville Campus
This work is licensed under a Creative Commons Attribution 4.0 International License.
Based on a work at https://cwoer.ccbcmd.edu/science/microbiology/index_gos.html..

Last updated: August, 2019
Please send comments and inquiries to Dr. Gary Kaiser